Published

  • P R.O'Neill, L. Giri, W. K. Ajith Karunarathne, A. K. Patel., K.V. Venkatesh and N. Gautam, "The structure of dynamic GPCR signaling networks" WIRES Systems Biology and Medicine, 6(1): 115-123, 2013. Imapact factor: 3.676

  • W. K. Ajith Karunarathne, L. Giri, A. K. Patel., K. V. Venkatesh, and N. Gautam, "Optical control demonstrates switch-like PIP3 dynamics underlying the initiation of immune cell migration" Proceedings of the National Academy of Sciences, 110(17):E1575-83, 2013. Impact factor: 9.68

  • W. K. Ajith Karunarathne, L. Giri, V. Kalyanraman, and N. Gautam, "Optically triggering spatiotemporally confined GPCR activity in a cell and programming neurite initiation and extension" Proceedings of the National Academy of Sciences, 110 (17) E1565-E1574 , 2013. Impact factor: 9.68

  • L. Giri, M. Feiss, B. C. Bonning, and D. W. Murhammer "Production of baculovirus defective interfering particles during serial passage is delayed by removing transposon target sites in fp25k," Journal of General Virology, 93:2, 389-399, 2012. Impact factor: 3.36

  • L. Giri, D. Sandgren, H. Li, M. Feiss, R. Roller, B. C. Bonning , and D. W. Murhammer, "Removal of transposon target sites from the AcMNPV fp25k gene delays, but does not prevent, accumulation of the few polyhedra phenotype," Journal of General Virology 91:12 3053-3064, 2010. Impact factor: 3.36

  • L. Giri, V. K. Mutalik and K. V. Venkatesh, "A steady state analysis indicates that negative feedback regulation of PTP1B by Akt elicits bistability in insulin-stimulated GLUT4 translocation," Theoretical Biology and Medical Modeling, 1:2 2004. Impact factor: 1.86

In Preparation

  • L. Giri, A. K. Patel, W.K. Ajith Karunarathne, V. Kalyanaraman, K.V. Venkatesh and N. Gautam,"G-protein subunit translocation embedded network motif underlies GPCR regulation of Calcium oscillations, (submitted), Biophysical journal

  • L. Giri, M. Feiss, B. C. Bonning, and D. W. Murhammer “Heterogeneous ultrastructural characteristics of AcMNPV passaged in cell culture and new phenotypes for AcMNPV mutants", to be submitted in Quantitative Biology.

Conference Presentations

  • L. Giri , D. W. Murhammer, M. Feiss, Quantitative Assay to Measure the Defective Interfering Particles In Baculovirus Stock, Second International Conference on Accelerating Biopharmaceutical Development, Coronado Island, CA, Mar. 2009.

  • L. Giri, D. Sandgren, H. Li, D. W. Murhammer, B. C. Bonning, M. Feiss, R. Roller, Analyzing and Overcoming of Baculovirus Mutants Obtained from Passaging In Insect Cell Culture. A Potential Approach to Low-Cost and Large-Scale Baculovirus Production, AICHE Annual Meeting, Food, Pharmaceutical & Bioengineering Division: Green Biotechnology, Philadelphia, PA, Nov. 2008.

  • L. Giri, D. Sandgren, H. Li, D. W. Murhammer, B. C. Bonning, M. Feiss, R. Roller, Removal of transposon target sites from AcMNPV fp25k delayed incidence of the FP phenotype but had no impact on DIP production in cell culture, 41st Annual Meeting of the Society for Invertebrate Pathology and 9th International Conference on Bacillus thuringiensis, Virus division, University of Warwick, Coventry, U.K., Aug. 2008.

  • L. Giri, D. W. Murhammer, B. C. Bonning and M. Feiss, Overcoming mutations in fp25k baculovirus gene on the way to continuous biopesticide production in insect cell culture, ACS Annual meeting, New Developments and Issues in Agrochemical Sciences, Boston, MA, Aug. 2008.

  • L. Giri and D. W. Murhammer, Construction of an insect cell line having viral gene fp25k: A Potential Remedy for FP Mutation in large-scale baculovirus production, First International Conference on Accelerating Biopharmaceutical Development, Rapid cell line development and improved expression system development, Coronado Island, CA, Mar. 2007.

  • L. Giri, and K V Venkatesh, Dynamic modeling and simulation of Insulin signaling pathway, Mathematical Bioengineering, Ohio State University, Ohio, 2007.

  • L. Giri, J. Baker, H. Wang, M Ehsani, A Lin, Y Qian, T Hieronymus, Ba Ring, S Wrighton, Y. Guo, Functional analysis of human CYP enzyme alleles, Eli Lilly and Company: Intern poster session, Indianapolis, IN, Jul. 2007.

  • L. Giri, D. W. Murhammer, B. C. Bonning and M. Feiss Overcoming Mutations in the fp25k Baculovirus Gene, Baculovirus Technology, Boston, MA, Sep. 2007.

  • L.Giri and D.Murhammer, Overcoming mutations in fp25k baculovirus gene on the way to continuous biopesticide production, Center for Bioprocessing and Biocatalysis Annual conference Iowa city, IA, Oct. 2006.

  • L.Giri and D.Murhammer, Overcoming mutations in fp25k baculovirus gene on the way to continuous biopesticide production, Research Open House, University of Iowa, Iowa city, IA, Apr. 2006.

  • L. Giri, D. W. Murhammer, B. C. Bonning and M. Feiss, Towards Continuous Biopesticide Production in Insect Cell Culture: Overcoming Mutations in Fp25k Baculovirus Gene, AICHE Annual Meeting, Food, Pharmaceutical & Bioengineering Division, San Francisco, CA, Nov. 2006.

  • L. Giri, D. W. Murhammer, B. C. Bonning and M. Feiss, Towards continuous biopesticide production in insect cell culture: overcoming mutations in fp25k baculovirus gene, All Iowa Virology Symposium, Iowa City, IA, Oct. 2006.

  • L.Giri, K.V. Venkatesh, Dynamic Modeling & Simulation of Insulin Signaling Pathway, Indian Chemical Engineering Congress (CHEMCON), Delhi, India, Dec. 2005.